If you don’t like BÉPO because you want familiar letter-based clipboard shortcuts, you’ve already made a better layout selection impossible. I learned to use the older clipboard shortcuts: ctrl+ins for copy, shift+ins for paste, and shift+del for cut. Those are still as universally supported.
I use them fine with my left hand. There’s no reason to stay on home row if you’re doing a lot of copy and paste. Of course, if you’re doing that much copy and paste, using an extension that allows VIM shortcuts would be much faster.