This is mostly what I use too. Additionally, on images with high ISO I usually add the profiled denoise module, often without changing the default values. If the image has a lot of noise, I sometimes use the preset that only reduces chroma noise (so the image stays grainy, but without the color mismatches)
In my experience, that is usually a problem with the GPU OpenCL drivers. Sadly, the Mesa OpenCL implementation didn’t include image support when I last checked (you can check with
clinfo | grep "Image support"). For AMD cards you need to have either the “pro” driver or ROCM installed, both aren’t packaged by all distros. Similar with Intel, don’t know about Nvidia, but I’m sure if it works, it’s only with the proprietary driver.I ended up installing darktable in an arch distrobox container, as arch has ROCM packages (in AUR) and ever since GPU acceleration is working fine.